11. Marinate chicken pieces in buttermilk for 8-12 hours in refrigerator.
22. Combine flour, paprika, garlic powder, onion powder, cayenne, salt, and black pepper in large mixing bowl.
33. Remove chicken from buttermilk, allowing excess to drip off. Dredge each piece thoroughly in seasoned flour mixture, pressing coating firmly into chicken.
44. Heat vegetable oil in heavy cast-iron skillet to 325°F. Oil should be 2-3 inches deep.
55. Carefully place coated chicken pieces into hot oil, avoiding overcrowding. Fry in batches until golden brown and internal temperature reaches 165°F, about 12-15 minutes.
66. Remove chicken using slotted spider, drain on wire rack with paper towels underneath.